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PE-22-28

Nootropic & CognitiveResearch Use Only

Also known as: Spadin analog

A fragment of the brain peptide spadin, studied as a fast-acting research antidepressant.

Dosing quick reference

research reference
Starting dose
50 mcg once daily
Frequency
Once daily
Typical range
50–200 mcg per day
Cycle
12–16 weeks (8 minimum)
Titration (step-up)
Wk 1–2: 50 → Wk 3–8: 100 → optional 150–200 mcg
Half-life
Short
Route
Subcutaneous or intranasal (research)
Common use
Mood and neuroplasticity research
Common vial sizes
10 mg
Storage
Store lyophilized powder frozen; after reconstitution refrigerate at 2-8°C and use within a few weeks.

Reported side effects

Limited human data availablePossible injection-site irritation
Calculate a dose →PE-22-28 on The Peptide Guide →Deeper research reference: literature dose ranges, storage and handling, and where to source in Canada.

Dose figures are ranges commonly referenced in research literature, not recommendations or medical advice. Research-only labeling does not establish that a substance is safe, approved or appropriate for personal use. Consult a qualified healthcare professional about health decisions.