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AICAR

Mitochondrial & MetabolicResearch Use Only

Also known as: Acadesine, AICA ribonucleotide, ZMP

An exercise-mimicking molecule that switches on the same energy sensor training does (AMPK). WADA-banned in sport.

Dosing quick reference

research reference
Starting dose
1 mg once daily
Frequency
Once daily
Typical range
1–3 mg per day
Cycle
8–12 weeks
Titration (step-up)
Wk 1–2: 1 mg → Wk 3–4: 2 mg → Wk 5+: 3 mg
Prohibited by WADA for athletes.
Half-life
Short (reported in preclinical data)
Route
Subcutaneous (research)
Common use
AMPK-pathway and metabolic research
Common vial sizes
50 mg
Storage
Store lyophilized powder refrigerated (2–8°C) and protected from light; once reconstituted, keep refrigerated and use within the timeframe supported by stability data.
Stacking notes
Sometimes referenced alongside other metabolic research compounds; combinations are not well characterized. Note AICAR appears on anti-doping prohibited lists.

Reported side effects

Limited human safety dataCellular effects reported in preclinical studies
Regulatory note: Not approved as a therapeutic drug in Canada or the US; research compound and listed as a prohibited substance in sport by anti-doping authorities. Research-grade material is not for human use.
Calculate a dose →AICAR on The Peptide Guide →Deeper research reference: literature dose ranges, storage and handling, and where to source in Canada.

Dose figures are ranges commonly referenced in research literature, not recommendations or medical advice. Research-only labeling does not establish that a substance is safe, approved or appropriate for personal use. Consult a qualified healthcare professional about health decisions.