AICAR

Mitochondrial & MetabolicResearch Use Only

Also known as: Acadesine, AICA ribonucleotide, ZMP

AICAR is a research compound commonly referenced in metabolic and exercise-physiology literature as an activator of AMP-activated protein kinase (AMPK). Studies describe interest in AMPK activation in relation to cellular energy sensing and glucose uptake in preclinical models. It is used primarily as a research tool.

Typical range (research)

Referenced primarily in preclinical research; no established human reference range

Half-life

Short (reported in preclinical data)

Route

Subcutaneous (research)

Common use

AMPK-pathway and metabolic research

Common vial sizes

50 mg

Storage

Store lyophilized powder refrigerated (2–8°C) and protected from light; once reconstituted, keep refrigerated and use within the timeframe supported by stability data.

Stacking notes

Sometimes referenced alongside other metabolic research compounds; combinations are not well characterized. Note AICAR appears on anti-doping prohibited lists.

Reported side effects

Limited human safety dataCellular effects reported in preclinical studies

Regulatory note: Not approved as a therapeutic drug in Canada or the US; research compound and listed as a prohibited substance in sport by anti-doping authorities. Research-grade material is not for human use.

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Dose figures are ranges commonly referenced in research literature, not recommendations or medical advice. Not for human or veterinary use. Consult a licensed physician.