Personal record-keeping and educational reference. 18+. The app does not recommend substances, doses or treatment, or determine whether a substance is safe, approved or appropriate for you. Consult a qualified healthcare professional about decisions involving your health.

Semaglutide reconstitution calculator

Calculate volume and syringe units for Semaglutide from the values you enter. Outputs do not determine a suitable dose or verify your inputs. Free, no account needed.

Peptide in vial
BAC water added
mL
Dose per injection
Draw to
5.0U
on a U-100 · 1 mL insulin syringe
0 U255075100 U
5mg / mL
0.05mL / injection
40doses / vial

Draw 5 units (0.05 mL) on a U-100 · 1 mL for a 0.25 mg dose. Each vial gives about 40 doses.

Save this to a protocol →

Arithmetic based on the values you enter. Outputs do not determine a suitable dose or verify your inputs. Free account: save your protocol and log doses. Pro adds scheduled email reminders, inventory estimates, and trends — 7-day free trial. The calculator stays free forever.

How to use this Semaglutide calculator

  1. Enter the vial size printed on your label — Semaglutide is commonly sold as 5 mg, 10 mg, 20 mg.
  2. Enter the bacteriostatic water you added, in mL.
  3. Enter your dose, in mg.
  4. Pick your syringe — the units, fill bar and warnings all adjust to it.

Worked example

A 10 mg Semaglutide vial reconstituted with 2 mL of bacteriostatic water gives a concentration of 5 mg/mL. A 0.25 mg dose is 0.05 mL — which is 5 units on a U-100 insulin syringe, and about 40 doses per vial.

The calculator above is already loaded with these numbers. Change any field to match your own vial.

Typical range (research)
Research literature commonly references escalating weekly amounts in the ~0.25–2.4 mg/week range
Half-life
~7 days
Route
Subcutaneous (research)
Common vial sizes
5 mg · 10 mg · 20 mg
Storage
Store lyophilized powder refrigerated (2–8°C) and protected from light; once reconstituted, keep refrigerated and use within the timeframe supported by stability data.

Common questions

How many units is 0.25 mg of semaglutide?

It depends entirely on your concentration — 'units' measure volume, not peptide. On a 10 mg vial reconstituted with 2 mL (5 mg/mL), 0.25 mg is 0.05 mL, which reads as 5 units on a U-100 insulin syringe. Change the water and the unit count changes even though the dose does not. The calculator performs this arithmetic from your inputs; it does not verify them or determine dose suitability.

Does adding more bacteriostatic water make the dose weaker?

No. It dilutes the concentration, so you draw a larger volume for the same amount of peptide. The milligrams you receive are unchanged — only the number on the syringe moves.

Why do research protocols escalate the amount over time?

Published trials commonly start low and step up over several weeks. Literature attributes this to tolerability, particularly gastrointestinal effects. This is a description of trial design, not a recommendation.

Regulatory note: Prescription drug in Canada and the US; approved for type 2 diabetes and chronic weight management under brand names. Research-grade material is not for human use.

Dose figures are ranges commonly referenced in research literature — not recommendations or medical advice. Arithmetic uses the values entered; it does not determine a suitable dose or verify your inputs. Research-only labeling does not establish that a substance is safe, approved or appropriate for personal use. Verify calculations independently and consult a qualified healthcare professional about health decisions.